Not all enzyme blends are created equal. There are only a handful of enzyme formulations that actually work. Enzyme potency is measured by activity levels. A systemic enzyme supplement, such as Neprinol, is measured by "FUs" or Fibrinolytic Units. With most enzyme blends, a typical serving size is 1-2 capsules, providing an average of 1,000-2,000 FUs...however, some of the higher-end enzyme blends can provide up to 15,000 FUs per capsule, yielding much higher activity levels.
Simply adding more milligrams of an enzyme does not necessarily increase the product's potency. When choosing an enzyme blend, look carefully for the activity rating rather than the milligrams per serving, which only indicates the individual components of the blend by their weight as opposed to their strength.
No serious or adverse side effects have been reported from taking systemic enzymes. Clinical studies have shown that even extremely large doses of these enzymes are not toxic. Even after prolonged use at high dosages, enzymes are more easily tolerated in the body than other dietary supplements like Vitamin C or E. If you are taking prescription blood-thinning medication, you should consult your physician before taking a systemic enzyme formula.