The first stage is what we refer to as Enzymatic Detoxification. During this period, your body is first introduced to enzymes. A systemic enzyme formula, like Neprinol, will begin by thinning the blood and removing excessive toxicity that your body has built up. Years of buildup on the inside of artery walls, as well as the mucosa of the colon and gastrointestinal system are stripped away and excreted. During this period you may experience mild headaches, fatigue, pungent urine, vaginal spotting, softened stool or diarrhea.