FibroVera

Account Login

Cart

Site Map

Natural health supplements, alternative medicines, enzymes, probiotics and more!

World Nutrition Vitalzym, Proteolytic Enzymes, Probiotic Supplements, Neprinol Wholesale Pricing

Systemic Enzymes, Discounted Vitalzym, Natural Health Supplement Sales, Neprinol Distributors

Natural Treatments For Leaky Gut, Fibromyalgia Pain Treatment, Enzyme Distributors

What Are Enzymes? How Will Enzymes Benefit Your Overall Health?

Southwest Nutraceuticals Auto-Ship Program with 10% Off

Southwest Nutraceuticals official blog: Neprinol, enzymes, probiotics, pain relief

Contact Information for Southwest Nutraceuticals in Phoenix, Arizona

Free Shipping!
on orders over $50
*United States Only

Click here for BBB Business Review

Order Online
24 hours a day,
7 days a week,
365 days a year!

Hours of Business:
Monday-Friday 8am-5pm
(Mountain Time)

Call Us Toll Free
1-800-959-8872

(In Arizona)
602-296-4641

Email Us
sales@swnutra.com

Follow Us On

Southwest Nutraceuticals

Promote Your Page Too

From the makers of Neprinol, Syntol, and Devacor!

FibroVera 730mg / 90 caps

Reg. Price:

~~$99.99~~

Sale Price:

$69.99

Save:

$30.00

Click here for Frequently Asked Questions about FibroVera

Andrew L. Rubman, N.D.

Naturopathic Physician
Southbury Clinic for Traditional Medicines
CT, USA

Dr. Andrew L. Rubman is a naturopathic physician and founder of the Southbury Clinic for Traditional Medicines in Connecticut. He is a member of the American Association of Naturopathic Physicians and was inducted into the association's elite Founder's Club. He is also a Fellow of the International Association for Medical Preventics and a member of the National Center for Homeopathy, the Orthomolecular Medical Society, and the National Science Honor Society. His most current project has landed him as the primary formulator of Estromin® AHS, a unique blend of botanical components clinically documented to restore hormonal balance in woman. Estromin®, combined with fibrinolytic enzymes, provides women with a direct defense against uterine and breast abnormalities.

Hormonal Imbalances

As a Naturopathic Physician specializing in peri- and post-menopausal endocrinology, I have sought to address and manage the transition into and through menopause for hundreds of women challenged by a constellation of symptoms. The concepts of hormonal management and wellness support are not only clinically significant strategies but necessary components of care that have been accepted by clinicians and researchers as well. Over the years, I have prescribed varying regimes to address individual issues but have remained unsatisfied with the tools available to adequately control inflammation and its by-product: fibrin deposition. Advances in development and commercialization of superior fibrinolytic (fibrin dissolving) enzymes, specifically Nattokinase NSK� (a proprietary nattokinase) and Peptizyme� SP (a proprietary serratiopeptidase) have lead me to accept the task of working with the premier domestic enzyme formulator, Arthur Andrew Medical, to develop FibroVera�.

FibroVera is intended to dramatically improve the function of inherent processes in a woman's body that work to quench inflammation and enhance the dissolution of fibrin. To do this the formula must work in a number of ways: The components should operate in synergy with one another; each must have strong clinical support and preferably good research evidence for its intended effect; and finally, the resulting supplement should be able to be safely used by middle-aged women without significant interaction with other pharmacy or generate health concerns. I cannot emphasize strongly enough that it is my hope that women taking FibroVera share this with their treatment team and insist that there is responsible oversight for the totality of their care.

Estrogen Dominance

The phenomena of Estrogen Dominance has been widely discussed in the popular and professional literature as a prime contributor to the dysregulation on normal function experienced by not only women approaching, transitioning, and resolving the effects of menopause, but those young women experiencing difficulty with menarche (the beginning of fertility). This imbalance is initially characterized by a number of factors: a decrease in DHEA due to stress, aging, poor diet, side effects of prescriptive pharmacy etc.; a decrease in progesterone effect due to absolute decrease in synthesis secondary to adequate cholesterol down-conversion, insensitivity of progesterone receptors, and finally activation of a cross-conversion pathway that forces progesterone to act as a source for the synthesis of estrogens decreasing both its bioavailability as a hormone and as a substrate for the formation of adrenal cortical hormones.

This concept, unfortunately like most of endocrinology, is difficult for the average person to really understand. Believe me that most physicians struggle as well in that rather than distinct cause and effect, groups of influences serve to act together to influence components of the balancing system rather than predictably drive it in one way or another. Why is this concept important? To demonstrate that the best way to not only address the conditions and symptoms associated with dysregulation, such as abnormal tissue growth and inflammation, is by providing the body with tools that it can use to enhance processes that it already has in place to decrease symptoms and potentially undo tissue changes.

That's correct. Given the proper support a woman's body can potentially not only control but reverse the growth of fibrous tissue in circulation, in arterial plaque, and in fibrous breasts, but do the same with degenerating joints, major skeletal muscles, and even fibroid tumors. Granted that this is a tall order and rather than make broad pronouncements, why not focus on a particular group and design a formulation specifically tailored to them. This is precisely why I chose to develop FibroVera with Arthur Andrew Medical.

Simply, chronic inflammation supports fibrosis which under the influence of hormonal dysregulation leads to fibrin deposition as plaque, fibroid cysts and tumors, cavity inflammation with adhesions like endometriosis and PID, and diminished functionality and longevity across almost all tissue lines. If you were to ask me about the field of "Anti-aging Medicine", I would tell you to start here. Even the efficacy of the estrogens in activating receptors in bone tissue, a factor contributing to osteoporosis is compromised by these imbalances and substrate issues.

FibroVera for a Lifetime of Uterine and Breast Health

Estrogen stimulates tissue growth, and progesterone signals the body to slough it off. When a woman's progesterone to Estrogen levels are balanced the normal ovulation cycle continues until menopause. Two common scenarios exist that can interrupt this balance: estrogen can be introduced to the body through outside or environmental factors, such as diet and chemical exposure, causing estrogen to dominate. The scenario is Progesterone levels begin to naturally diminish with age and again estrogen becomes the dominant hormone. Without enough "opposing" progesterone, estrogen levels stay unnaturally high in the second half of the menstrual cycle. Growth factors that are stimulated in preparation for pregnancy are not deactivated by the proper amount of progesterone and can lead to abnormal tissue growth in the uterus.

Fibrin (scar tissue) the key building block of tissue repair binds with endometrial muscle in preparation for pregnancy. In a woman with an ideal ratio of progesterone to estrogen, progesterone will inhibit these growth factors and reverse this growth. Fibrin can be directly metabolized by introducing Fibrinolytic (fibrin lysing) enzymes. These enzymes are bioidentical to plasmin the body's natural Fibrinolytic enzyme. The Fibrinolytic enzyme Nattokinase is actually 60% stronger than plasmin itself.

When either progesterone is deficient or estrogen is in excess the uterus tends to bind with excess fibrin and form abnormal growths such as endometriosis and fibroids. Fortunately Fibrinolytic enzymes are able to digest these growths, but in order to restore the natural progesterone to Estrogen ratio many more factors need to be introduced to the body.

What Makes Fibrovera Different than other Natural Remedies?

Why FibroVera? I should briefly tell you about my clinical experience with the components and how I brought down the typical clinically effective dosage by utilizing a synergistic approach. The "prime movers" in the formula are the two enzymes mentioned at the start of this piece, Nattokinase NSK, and Peptizyme SP. Research and clinical studies support the claims that Nattokinase NSK and Peptizyme SP helps the body dissolve fibrin including plaque that has already been deposited and organized and quench inflammation in tandem with each other.

- The bromelain and papain are carry-overs from FibroVera's predecessors, what I refer to as "Wobenzym® inspired formulae". They reduce inflammation, swelling, and micro-trauma and support aggressive fibrinolysis instigated by the Nattokinase NSK and Peptizyme SP.

- Calcium and magnesium adequacy are essential to pain modulation and pain perception modulation as well as cramping and other PMS-like symptoms. Why calcium caprylate? Calcium absorption from the gut is tricky, providing a "butter-fat salt" form allows it to be completely taken up into the system within an hour. And this caprylate component exerts an anti-yeast effect beneficial to the healing process of many tissues.

- Why magnesium ammoniate? Providing a well-absorbed magnesium source with the added benefit of a physiologic acid-quencher like ammoniate seemed like a clear choice.

- Co-Enzyme Q10, or CoQ10 as it is known, is known to modulate neuromuscular coordination as it does in increasing "ejection fraction" in many cardiac patients. It is included in FibroVera because I have found that due to this capacity and its anti-oxidant functions, it is useful in quenching inflammation and easing the pain and dysfunction in tissue compromised with fibrin deposition.

- GLA works so well in the Clinic at relieving much of the "PMS" associated symptomatology, including breast, joint and muscle tenderness that it was an essential ingredient.

- DIM is a great extract from the Brassica family of cruciferous vegetables that has been shown to modulate estrogen metabolism allowing the body to preferentially create more healthy products like 16-á OH-estrogens and less 2-á OH-estrogens. Without boring you with the details, this is extremely significant to Naturopathic Oncologists concerned about maintaining positive estrogen effects while avoiding promoting those disruptive ones. I have noted in my clinic and association between the management of fibroid and the use of DIM in therapeutic regimes.

- Although few Western studies evaluating Dong Quai exist, it has been revered in Traditional Chinese Medicine for its ability to modulate the effects of what we would call "hormonal transitions and challenges". Translated from a prominent Chinese medical text, Dong Quai "returns order and harmonizes vital energy" (Now that's inscrutable!).

- The next component was the trickiest, DHEA. I have studied the literature and incorporated it into treatment regime for over a decade and now feel comfortable enough about its metabolism and effects to include it in an OTC formula. Yes it is a steroidal hormone precursor, however at the dosage levels supplied, it can be regarded as underwriting the proper synthesis of the estrogens and testosterone as well as the balance and effects of a myriad of neurotransmitter in the central nervous system. It is included at synergistic dose levels to help the individual not only do better, but feel better as well.

*The final bevy of ingredients: milk thistle seed extract, dandelion, and hyssop are included under the general heading of liver tonics. This function impacts the breakdown and removal of hormonal metabolites as well as pro-inflammatory substances that can frustrate our intended task.

Click here for Frequently Asked Questions about FibroVera

FibroVera 730mg / 90 caps

Reg. Price:

~~$99.99~~

Sale Price:

$69.99

Save:

$30.00

Page References

[1] Kordon C, Gallard R, Christen Y. (2005). Research and Perspectives in Endocrine Interactions

Hormones and the Brain (pp. 79-98). New York, NY: Springer.

[2] Ashok BT, Chen Y, Liu X, Bradlow HL, Mittelman A, Tiwari RK. Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol. Nutr Cancer 2001;41(1-2):180-7.

[3] Ashok BT, Chen YG, Liu X, Garikapaty VP, Seplowitz R, Tschorn J, Roy K, Mittleman A, Tiwari RK. Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer. Eur J Cancer Prev. 2002 Aug;11 Suppl 2:S86-93.

[4] Broadbent TA, Broadbent HS. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part II]. Curr Med Chem 1998 Dec;5(6):469-91.

[5] Tiwari RK, Guo L, Bradlow HL, Telang NT, Osborne MP. Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent. J Natl Cancer Inst 1994 Jan 19;86(2):126-31.

[6] Edelstam G, Lecander I, Larsson B, Astedt B. Fibrinolysis in the peritoneal fluid during adhesions, endometriosis, and ongoing pelvic inflammatory disease. Inflammation, Vol. 22, No. 4, 1998.

[7] Mazzone A, Catalan M, Costanzo M, Drusian A, Mandol A, Russo S, Guarini E, Vesperini G. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990 Sep-Oct;18(5):379-88.

[8] Tachibana M, Mizukosi 0, Harada Y, Kawamoto K, Nakai Y. A multi-centre, double-blind study of serrapeptase versus placebo in post-antrotomy buccal swelling. Pharmatherapeutica, 3(8):526-30 1984.

[9] Mazzone A, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990; 18(5):379-88.

[10] Aso T et al. Breast engorgement and its treatment: Clinical effects of Danzen an anti-inflammatory enzyme preparation. The World of Obstetrics and Gynecology (Japanese). 1981; 33:371-9.

[11] Nakamura S, et al. Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease. Respirology Vol 8 #3, Sept 2003, p.316-320 doi:10.1046/j.1440-1843.2003.00482.

[12] Stange R, Schneider R, Maurer R, and et al. Proteolytic enzyme bromelain enhances cytotoxicity in patients with breast cancer [abstract]. National Scientific Conference on Complementary, Alternative & Integrative Medicine Research, April 12 - 14 2002.

[13] Kleine MW. Introduction to oral enzyme therapy. Int J Immunotherapy 1997;13(3-4):59-65.

[14] Smyth RD, Brennan R, Martin GJ. Studies establishing the absorption of the bromelains (proteolytic enzymes) from the gastrointestinal tract. Exp Med Surg 1964;22:46-59.

[15] Glenn J. Managing a traumatic wound in a geriatric patient. Ostomy Wound Manage 2006;52(4):94-8.

[16] Sumi H, Hamada H, Nakanishi K, Hiratani H. Enhancement of the Fibrinolytic Activity in Plasma by Oral Administration of Nattokinase1 Acta Haematol 1990;84:139-143.

[17] Sumi H, Hamada H, Mihara H, Nakanishi K, Hiratani H. Fibrinolytic effects of the Japanese traditional food "natto" (Natokinase). Japan Thromb Haemostas 62: 549, 1989.

[18] Sumi H, Hamada H, Tsushima H, Mihara H, A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese natto: A typical and popular soybean food in the Japanese diet. Experimentia 43:1110-1111(1987).

[19] Gaby AR. Dehydroepiandrosterone: biological effects and clinical significance. Alt Med Rev 1996;1(2):60-69.

[20] Haning RV Jr., Austin CW, Carlson IH, Kuzma DL, Zweibel WJ. Role of dehydroepiandrosterone sulfate as a prehormone for ovarian steroidogenesis. Obstet Gynecol 1985;65(2):199-205.

[21] Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4(3):183-189.

[22] Witkowska D, Sedrowicz L, Oledzka R, Bialek A. The effects of zinc and magnesium on calcium uptake into the rat duodenum slices. Biol-Met 1989; 2(1): 36-39.

[23] Puolakka J, M�k�r�inen L, Viinikka L, Ylikorkala O. Biochemical and clinical effects of treating the premenstrual syndrome with prostaglandin synthesis precursors. J Reprod Med 1985 Mar;30(3):149-53.

[24] Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol 1991 Oct;30(5):370-2.

[25] Remans PH, Sont JK, Wagenaar LW, Wouters-Wesseling W, Zuijderduin WM, Jongma A, Breedveld FC, Van Laar JM. Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects. Eur J Clin Nutr 2004 Jun;58(6):839-45.

[26] Magnussen I, Nielsen-Kudsk F. Pharmacokinetics of intravenously administered L-5-hydroxytryptophan in man. Acta Pharmacol Toxicol (Copenh) 1979;44(4):308-314.

[27] van Praag HM, Korf J, Dols LC, Schut T. A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant. Psychopharmacologia 1972;25(1):14-21.

[28] Zarcone V, Kales A, Scharf M, Tan TL, Simmons JQ, Dement WC. Repeated oral ingestion of 5-hydroxytryptophan. The effect on behavior and sleep processes in two schizophrenic children. Arch Gen Psychiatry 1973;28(6):843-846.

[29] Puttini PS, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. J Int Med Res. 1992;20(2):182-189.

[30] Caruso I, Sarzi, Puttini P, Cazzola M, Azzolini V. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res 1990;18(3):201-209.

[31] Ribeiro CA. L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. Headache 2000;40(6):451-456.

[32] Kotani N, Oyama T, Sakai I, et al. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea--a double-blind study. Am J Chin Med 1997;25(2):205-212.

[33] Kronenberg F, Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med 11-19-2002;137(10):805-813.

[34] Zhiping H, Dazeng W, Lingyi S, et al. Treating amenorrhea in vital energy-deficient patients with angelica sinensis-astralagus membranaceus menstruation-regulating decoction. J Trad Chin Med 2002;6(3):187-190.

[35] Wyatt KM, Dimmock PW, Jones PW, et al. Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. BMJ 5-22-1999;318(7195):1375-1381.

[36] Sahakian V, Rouse D, Sipes S, Rose N, et al. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstet Gynecol 1991;78(1):33-36.

[37] Thaver D, Saeed MA, Bhutta ZA. Pyridoxine (vitamin B6) supplementation in pregnancy. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD000179.

[38] Mira ML, Azevedo MS, Manso C. The neutralization of hydroxyl radical by silibin, sorbinil and bendazac. Free Radical Res Commun 1987;4(125):129.

[39] Muzes G, Deak G, Lang I. Silymarin (Legalon) kezeles hatasa idult alkoholos majbetegek antioxidans vedorendszerere es a lipid peroxidaciora (kettos vak protokoll). Orvosi Hetilap 1990;131:863-866.

[40] Dehmlow C, Murawski N, de Groot H. Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. Life Sci 1996;58(18):1591-1600.

[41] Mascolo N, Autore G, Capasso F, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytotherapy Res 1987;1(1):28-31.

[42] Bohm K. Studies on the choleretic action of some drugs. Azneim-Forsh 1959;9:376-378.

[43] Hagymasi K, Blazovics A, Feher J, et al. The in vitro effect of dandelions antioxidants on microsomal lipid peroxidation. Phytother Res 2000;14(1):43-44.

[44] Varga E, Hajdu Z, Veres K, Mathe I, Nemeth E, Pluhar Z, Bernath J. Investigation of variation of the production of biological and chemical compounds of Hyssopus officinalis L.. Acta Pharm Hung 1998;68(3):183-188.

[45] Cesarone MR, Belcaro G, Pellegrini L, Ledda A, Di Renzo A, Vinciguerra G, Ricci A, Gizzi G, Ippolito E, Fano F, Dugall M, Acerbi G, Cacchio M. HR, 0-(beta-hydroxyethyl)-rutosides, in comparison with diosmin+hesperidin in chronic venous insufficiency and venous microangiopathy: an independent, prospective, comparative registry study. Angiology 2005;56(1):1-8.

Try FibroVera with Neprinol!

A great add-on to Neprinol, for women with severe fibroids!

To add Neprinol to a bottle of FibroVera,
choose a size from the drop-down list below:

SITE MAILING LIST

Receive email notifications, updates, and coupons when you sign up! Enter your email address and press the 'Go' button. **We do NOT sell or share your information with anyone or any companies.

WHOLESALE ACCOUNTS

Healthcare Professionals
and Retail Stores!

Please call 1-800-959-8872
for wholesale prices on the
Arthur Andrew Medical product line.

Wholesale Account Application

Natural Healthcare Distribution

Neprinol Syntol Devacor Vitalzym Neprofin Serracel FibroVera Proferia Optimal Vertical System Serra RX

BBB Seal

Southwest Nutraceuticals
PO Box 387
Higley, AZ 85236
Toll Free: 1-800-959-8872
(In Arizona): 602-296-4641
Email: sales@swnutra.com

Privacy Policy

We proudly accept the following cards

© 2004 - 2010 Southwest Nutraceuticals. All Rights Reserved.
Southwest Nutraceuticals is a trade name and d.b.a. of TJB Investing Corp.
The products and the claims made about specific products on or through this site have not been evaluated by Southwest Nutraceuticals or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.
*Prices are subject to change without notice*